anti-马 Caspase 1 抗体 for Western Blotting

Recommended Caspase 1 Antibody (supplied by: Log in to see )

抗原
Caspase 1 (CASP1) 抗体
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
抗原表位
Middle Region
36
16
14
10
10
10
10
9
8
7
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
马, 人, 兔, Yeast (Saccharomyces cerevisiae)
268
103
81
8
3
2
1
1
1
1
1
宿主

256
40
8
2
克隆类型
多克隆
标记
This Caspase 1 antibody is un-conjugated
23
16
8
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
275
167
123
85
32
27
19
15
7
5
3
3
1
选项
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

产品编号 ABIN2787901
$ 289.00
加上运输费 $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN575710 WB Rabbit AA 30-79 Log in to see Polyclonal 0

General

抗原 Caspase 1 (CASP1) 抗体
抗原表位 Middle Region
(36), (16), (14), (10), (10), (10), (10), (9), (8), (7), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 马, 人, 兔, Yeast (Saccharomyces cerevisiae)
(268), (103), (81), (8), (3), (2), (1), (1), (1), (1), (1)
宿主
(256), (40), (8), (2)
克隆类型
多克隆
标记 This Caspase 1 antibody is un-conjugated
(23), (16), (8), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Western Blotting (WB)
(275), (167), (123), (85), (32), (27), (19), (15), (7), (5), (3), (3), (1)
Supplier Log in to see

Caspase 1抗体详情

Caspase 1目标详情 使用细节 贮存及处理 图像
Blocking Peptide Blocking peptide for this product available: ABIN974471
序列 LQTRVLNKEE MEKVKRENAT VMDKTRALID SVIPKGAQAC QICITYICEE
预测反应 Horse: 79%, Human: 100%, Rabbit: 79%, Yeast: 100%
产品特性 This is a rabbit polyclonal antibody against CASP1. It was validated on Western Blot.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the middle region of human CASP1
Plasmids, Primers & others

Caspase 1目标详情

Caspase 1抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 CASP1 (CASP1 Antibody 摘要)
背景 This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
Alias Symbols: ICE, IL1BC, P45
Protein Interaction Partner: ced-3, ced-4, VAC14, BCL2L1, UBC, XK, PLA2G4B, IL33, IL1B, PARP1, BIRC3, TRAF2, CEBPB, TIRAP, CARD17, CARD16, CARD8, PLA2G4A, CDK11B, NLRP1, ATN1, ATXN3, PYCARD, NLRC4, NOD1, CASP14, RIPK2, PAK1, PARK2, NEDD4, BID, IL18, PSEN2, NFE2L2, AR, BCAP31, MAPT, L
Protein Size: 383
分子量 10 kDa
基因ID 834
NCBI登录号 NM_001223, NP_001214
UniProt P29466
途径 Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

使用细节

Caspase 1抗体详情 Caspase 1目标详情 贮存及处理 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 383 AA

限制 仅限研究用

贮存及处理

Caspase 1抗体详情 Caspase 1目标详情 使用细节 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

图像

Caspase 1抗体详情 Caspase 1目标详情 使用细节 贮存及处理 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500...