Histone H4 Antibodies
Epigenetics is the study of heritable cellular, and physiological traits by factors other than DNA sequence. Examples are simple chemical modifications, like methylation and acetylation to DNA and interacting partners. Since the basic structure of the respective nucleobase is retained, DNA methylation is not a genetic mutation but a modification. These changes are however they play a role in controlling how, where, and when certain genes are expressed.
Antibodies against Histone H4 Modifications
Position | Unmodified | Methylation | Di-Methylation | Tri-Methylation | Acetylation |
---|---|---|---|---|---|
Arginin 3 | Arg3 | H4R3m1 | H4R3m2 | - | - |
Lysine | |||||
Lysine 5 | Lys5 | - | - | - | H4K5ac |
Lysine 8 | Lys8 | - | - | - | H4K8ac |
Lysine 12 | Lys12 | - | - | - | H4K12ac |
Lysine 16 | Lys16 | - | - | - | H4K16ac |
Lysine 20 | - | H4K20m1 | H4K20m2 | H4K20m3 | H4K20ac |
Lysine 31 | - | H4K31m1 | - | - | - |
Lysine 59 | - | - | H4K59m2 | H4K59m3 | - |
Lysine 79 | - | H4K79m1 | H4K79m2 | - | - |
Lysine 91 | - | - | - | - | H4K91ac |