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Glycogen Synthase 1 抗体 (pSer640)

GYS1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN99926
发货至: 中国
  • 抗原 See all Glycogen Synthase 1 (GYS1) 抗体
    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
    抗原表位
    • 15
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer640
    适用
    • 58
    • 35
    • 29
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 58
    • 1
    克隆类型
    • 45
    • 14
    多克隆
    标记
    • 38
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Glycogen Synthase 1 antibody is un-conjugated
    应用范围
    • 38
    • 25
    • 12
    • 9
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    Human Muscle Glycogen Synthase phospho peptide corresponding to a region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
    亚型
    IgG
    Top Product
    Discover our top product GYS1 Primary Antibody
  • 应用备注
    This phospho specific polyclonal antibody was tested by immunoblotting and ELISA.  By ELISA the antibody was found to be reactive with the phosphorylated form of the immunizing peptide and minimally reactive with the non-phosphorylated form of the immunizing peptide.   Immunoblotting will detect human and mouse muscle glycogen synthase.  Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))
    别名
    Glycogen Synthase 1 (GYS1 产品)
    别名
    GSY antibody, GYS antibody, GYS1 antibody, zgc:63701 antibody, GYS2 antibody, Gys3 antibody, MGS antibody, glycogen synthase 1 antibody, glycogen synthase 1 (muscle) antibody, glycogen synthase 1, muscle antibody, GYS1 antibody, gys1 antibody, Gys1 antibody
    背景
    Anti-Glycogen synthase 1 pS640 is validated by IHC, Western Blot and ELISA. Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units.  Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000.  GS is subject to regulation through both allosteric and covalent modification and occurs in two forms:  the phosphorylated inactive form, and the dephos-phorylated active form.  GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phos-phorylate muscle glycogen synthase.  This antibody is specific for the phosphorylated form of GS at S640.   Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.
    Synonyms: Glycogen antibody, Glycogen synthase 1 (muscle) antibody, Glycogen synthase 1 antibody, Glycogen synthase1 antibody, GSY antibody, GYS 1 antibody, GYS antibody, GYS1 antibody, Starchsynthase muscle antibody
    基因ID
    2997
    UniProt
    P13807
    途径
    PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process
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