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PDX1 抗体

PDX1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5A5 unconjugated
产品编号 ABIN969553
发货至: 中国
  • 抗原 See all PDX1 抗体
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    适用
    • 119
    • 45
    • 34
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
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    • 2
    • 1
    • 1
    • 1
    宿主
    • 132
    • 8
    • 2
    小鼠
    克隆类型
    • 126
    • 16
    单克隆
    标记
    • 61
    • 13
    • 9
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    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
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    This PDX1 antibody is un-conjugated
    应用范围
    • 90
    • 67
    • 36
    • 20
    • 18
    • 14
    • 14
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PDX1 expressed in E. coli.
    克隆位点
    5A5
    亚型
    IgG1
    Top Product
    Discover our top product PDX1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Fernandez-Zapico, van Velkinburgh, Gutiérrez-Aguilar, Neve, Froguel, Urrutia, Stein: "MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36482-90, (2009) (PubMed).

  • 抗原
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    别名
    PDX1 (PDX1 产品)
    别名
    GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
    背景

    Description: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

    Aliases: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1

    分子量
    30.8 kDa
    基因ID
    3651
    HGNC
    3651
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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