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PPP1CA 抗体

PPP1CA 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 6D1 unconjugated
产品编号 ABIN969359
发货至: 中国
  • 抗原 See all PPP1CA 抗体
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    适用
    • 74
    • 41
    • 41
    • 16
    • 10
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 50
    • 23
    • 2
    • 1
    小鼠
    克隆类型
    • 53
    • 23
    单克隆
    标记
    • 54
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PPP1CA antibody is un-conjugated
    应用范围
    • 49
    • 26
    • 16
    • 12
    • 11
    • 10
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PPP1A expressed in E. coli.
    克隆位点
    6D1
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: "Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex." in: The EMBO journal, Vol. 26, Issue 6, pp. 1511-21, (2007) (PubMed).

    Eto, Kirkbride, Elliott, Lo, Brautigan: "Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions." in: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17806-15, (2007) (PubMed).

  • 抗原
    PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
    别名
    PPP1A (PPP1CA 产品)
    别名
    PP-1A antibody, PP1A antibody, PP1alpha antibody, PPP1A antibody, Ppp1c antibody, dism2 antibody, ppp1a antibody, wu:fc04c08 antibody, wu:fc09b07 antibody, wu:fc30g11 antibody, wu:fe05h08 antibody, zgc:85729 antibody, Ppp1ca antibody, fb18b03 antibody, fd20h04 antibody, wu:fb18b03 antibody, wu:fd20h04 antibody, wu:fl22a03 antibody, zgc:55744 antibody, zgc:76940 antibody, protein phosphatase 1 catalytic subunit alpha antibody, protein phosphatase 1, catalytic subunit, alpha isoform antibody, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, alpha isozyme antibody, protein phosphatase 1, catalytic subunit, alpha isozyme a antibody, protein phosphatase 1, catalytic subunit, alpha isozyme b antibody, PPP1CA antibody, Ppp1ca antibody, ppp1ca.L antibody, ppp1ca antibody, ppp1caa antibody, ppp1cab antibody
    背景

    Description: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Aliases: PP-1A, PPP1A, MGC1674, MGC15877, PP1alpha, PPP1CA

    分子量
    38 kDa
    基因ID
    5499
    HGNC
    5499
    途径
    M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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