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PEG10 抗体

PEG10 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4C10A7 unconjugated
产品编号 ABIN969349
发货至: 中国
  • 抗原 See all PEG10 抗体
    PEG10 (Paternally Expressed 10 (PEG10))
    适用
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    宿主
    • 44
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    小鼠
    克隆类型
    • 46
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    单克隆
    标记
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    This PEG10 antibody is un-conjugated
    应用范围
    • 47
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PEG10 expressed in E. coli.
    克隆位点
    4C10A7
    亚型
    IgG1
    Top Product
    Discover our top product PEG10 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

    Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

    Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

  • 抗原
    PEG10 (Paternally Expressed 10 (PEG10))
    别名
    PEG10 (PEG10 产品)
    别名
    EDR antibody, HB-1 antibody, MEF3L antibody, Mar2 antibody, Mart2 antibody, RGAG3 antibody, AA407948 antibody, Edr antibody, MyEF-3 antibody, paternally expressed 10 antibody, PEG10 antibody, Peg10 antibody
    背景

    Description: PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

    Aliases: Edr, HB-1, Mar2, MEF3L, Mart2, RGAG3

    分子量
    Isoform RF1 (37 kDa), RF1/RF2 (80 kDa)
    基因ID
    23089
    HGNC
    23089
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