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JAK3 抗体

JAK3 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H2 unconjugated
产品编号 ABIN969224
发货至: 中国
  • 抗原 See all JAK3 抗体
    JAK3 (Janus Kinase 3 (JAK3))
    适用
    • 88
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    人, 小鼠
    宿主
    • 85
    • 5
    小鼠
    克隆类型
    • 70
    • 20
    单克隆
    标记
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    This JAK3 antibody is un-conjugated
    应用范围
    • 50
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    • 8
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human JAK3 expressed in E. coli.
    克隆位点
    5H2
    亚型
    IgG1
    Top Product
    Discover our top product JAK3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Wood, Goodman, Uckun: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).

  • 抗原
    JAK3 (Janus Kinase 3 (JAK3))
    别名
    JAK3 (JAK3 产品)
    别名
    JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody
    背景

    Description: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

    Aliases: JAKL, LJAK

    分子量
    125 kDa
    基因ID
    3718
    HGNC
    3718
    途径
    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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