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Cyclin D1 抗体

CCND1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D8 unconjugated
产品编号 ABIN969007
发货至: 中国
  • 抗原 See all Cyclin D1 (CCND1) 抗体
    Cyclin D1 (CCND1)
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Cyclin D1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CCND1 expressed in E. coli.
    克隆位点
    3D8
    亚型
    IgG1
    Top Product
    Discover our top product CCND1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Kurihara, Oda, Ohishi, Kaneki, Kobayashi, Wake, Tsuneyoshi: "Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 2, pp. 225-34, (2010) (PubMed).

    Parafioriti, del Bianco, Barisani, Armiraglio, Peretti, Albisetti: "Increased p21 expression in chondrocytes of achondroplasic children independently from the presence of the G380R FGFR3 mutation." in: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, Vol. 14, Issue 5, pp. 623-30, (2009) (PubMed).

  • 抗原
    Cyclin D1 (CCND1)
    别名
    CCND1 (CCND1 产品)
    别名
    BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody
    背景

    Description: During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by acting as regulatory subunits of the Cdks. Early in the G1 phase of the cell cycle, cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2. In a recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Cyclin D1 is also involved in development and cancer. Cyclin D1 has also been linked to the development and progression of several cancers including breast, bladder, esophagus, and lung.

    Aliases: BCL1, PRAD1, U21B31, D11S287E, CCND1

    分子量
    33.7 kDa
    基因ID
    595
    HGNC
    595
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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