DYNLL1 抗体 (AA 1-89)
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- 抗原 See all DYNLL1 抗体
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
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抗原表位
- AA 1-89
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适用
- 人, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DYNLL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 交叉反应
- 人
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat PIN aa. 1-89
- 克隆位点
- 4-PIN
- 亚型
- IgG1
- Top Product
- Discover our top product DYNLL1 Primary Antibody
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster." in: Molecular and cellular biology, Vol. 16, Issue 5, pp. 1966-77, (1996) (PubMed).
: "PIN: an associated protein inhibitor of neuronal nitric oxide synthase." in: Science (New York, N.Y.), Vol. 274, Issue 5288, pp. 774-7, (1996) (PubMed).
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Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster." in: Molecular and cellular biology, Vol. 16, Issue 5, pp. 1966-77, (1996) (PubMed).
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- 抗原
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- 别名
- PIN (DYNLL1 产品)
- 别名
- DLC1 antibody, DLC8 antibody, DNCL1 antibody, DNCLC1 antibody, LC8 antibody, LC8a antibody, PIN antibody, hdlc1 antibody, dynll2 antibody, wu:fd56c09 antibody, zgc:73406 antibody, Dlc8 antibody, Dnclc1 antibody, Pin antibody, 8kDLC antibody, lc8 antibody, dlc1 antibody, dlc8 antibody, lc8a antibody, dncl1 antibody, dnclc1 antibody, dynll1a antibody, MGC68763 antibody, CDLC2 antibody, dynll1 antibody, dynll1b antibody, pin antibody, MGC89636 antibody, dynein light chain LC8-type 1 antibody, dynein, light chain, LC8-type 1 antibody, dynein light chain LC8-type 1 S homeolog antibody, dynein light chain LC8-type 1 L homeolog antibody, Dynein light chain 1, cytoplasmic antibody, DYNLL1 antibody, dynll1 antibody, Dynll1 antibody, dynll1.S antibody, dynll1.L antibody, dlc-1 antibody
- 背景
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PIN (protein inhibitor of nNOS) is a small protein of 89 amino acids initially described as a light chain subunit of dynein and as an inhibitor of the neuronal nitric oxide synthase isoform (nNOS). In vitro, PIN has been reported to bind to a unique nNOS domain encompassing amino acids 163-245. PIN inhibits nNOS activity and blocks the formation of the active nNOS dimer. Although ubiquitously expressed, PIN levels are reportedly highest in brain and testis. Immunolocalization studies in Drosophila melanogaster detected a cytoplasmic distribution of PIN. Partial-loss-of-function of PIN resulted in morphologic and developmental changes in the bristles, wings, and female sterility of D. melanogaster. Deletion of PIN resulted in lethality with the characteristic morphology of apoptotic cells. This antibody is routinely tested by western blot analysis.
Synonyms: Protein Inhibitor of nNOS - 分子量
- 10 kDa
- 途径
- M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
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