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C-JUN 抗体 (AA 26-175)

JUN 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 3-Jun unconjugated
产品编号 ABIN967904
发货至: 中国
  • 抗原 See all C-JUN (JUN) 抗体
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    抗原表位
    • 42
    • 41
    • 30
    • 29
    • 22
    • 16
    • 16
    • 15
    • 11
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-175
    适用
    • 378
    • 205
    • 188
    • 32
    • 28
    • 21
    • 17
    • 17
    • 16
    • 12
    • 12
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 小鸡, 犬
    宿主
    • 372
    • 14
    • 2
    小鼠
    克隆类型
    • 347
    • 41
    单克隆
    标记
    • 188
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This C-JUN antibody is un-conjugated
    应用范围
    • 268
    • 134
    • 121
    • 89
    • 57
    • 44
    • 43
    • 43
    • 41
    • 23
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    人, 小鸡, 犬, 大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse c-Jun aa. 26-175
    克隆位点
    3-Jun
    亚型
    IgG2a
    Top Product
    Discover our top product JUN Primary Antibody
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Doray, Ghosh, Griffith, Geuze, Kornfeld: "Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network." in: Science (New York, N.Y.), Vol. 297, Issue 5587, pp. 1700-3, (2002) (PubMed).

    He, Stepulak, Holmström, Omary, Eriksson: "The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase." in: The Journal of biological chemistry, Vol. 277, Issue 13, pp. 10767-74, (2002) (PubMed).

    Chang, Nakajima, Illenye, Lee, Honjo, Makiyama, Fujiwara, Mizuta, Sawai, Saida, Mitsui, Heintz, Magae: "Caspase-dependent apoptosis by ectopic expression of E2F-4." in: Oncogene, Vol. 19, Issue 41, pp. 4713-20, (2000) (PubMed).

    Taupin, Wu, Jeon, Devaney, Wang, Podolsky: "The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation." in: The Journal of clinical investigation, Vol. 103, Issue 9, pp. R31-8, (1999) (PubMed).

    Lamph, Wamsley, Sassone-Corsi, Verma: "Induction of proto-oncogene JUN/AP-1 by serum and TPA." in: Nature, Vol. 334, Issue 6183, pp. 629-31, (1988) (PubMed).

  • 抗原
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    别名
    Jun (JUN 产品)
    别名
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    背景
    The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the SV40 virus and the human metallothionein IIA gene. AP-1 is composed of protein products of two different gene families: jun and fos. The AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins. The transcriptional activity of Jun is enhanced by phosphorylation in its activation domain at Ser63 and Ser73. Phosphorylation at both sites is necessary for stimulating the activating function of Jun. Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity. This antibody is routinely tested by western blot analysis.
    分子量
    39 kDa
    途径
    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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