(3 references)-
- 抗原 See all SRSF2 抗体
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SRSF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Partially purified spliceosomes
- 克隆位点
- AlphaSC35
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SRSF2 Primary Antibody
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anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (AA 1-75) antibody
SRSF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (C-Term) antibodySRSF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 小鸡, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (AA 9-39), (N-Term) antibodySRSF2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17329 unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (AA 14-221) antibodySRSF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (AA 1-179) antibodySRSF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (C-Term) antibodySRSF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) (N-Term) antibodySRSF2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Staining is nuclear, a punctate or speckled nuclear pattern may be detected. Only a subset of cells are stained, the percentage may vary between cell type and experimental conditions. MG-63 human osteosarcoma, HeLa carcinoma (ATCC CCL-2), or BRL-3A rat liver cells (ATCC CRL-1442) are suggested as positive controls.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15702-6, (1995) (PubMed).
: "Specific commitment of different pre-mRNAs to splicing by single SR proteins." in: Nature, Vol. 365, Issue 6441, pp. 82-5, (1993) (PubMed).
: "Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus." in: Nature, Vol. 343, Issue 6257, pp. 437-41, (1990) (PubMed).
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: "A putative mammalian RNA helicase with an arginine-serine-rich domain colocalizes with a splicing factor." in: The Journal of biological chemistry, Vol. 270, Issue 26, pp. 15702-6, (1995) (PubMed).
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- 抗原
- SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))
- 别名
- SC35 (SRSF2 产品)
- 别名
- PR264 antibody, SC-35 antibody, SC35 antibody, SFRS2 antibody, SFRS2A antibody, SRp30b antibody, D11Wsu175e antibody, MRF-1 antibody, Pr264 antibody, Sfrs10 antibody, Sfrs2 antibody, pr264 antibody, sc-35 antibody, sc35 antibody, sfrs2 antibody, sfrs2a antibody, srp30b antibody, serine and arginine rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 antibody, serine/arginine-rich splicing factor 2 L homeolog antibody, SRSF2 antibody, Srsf2 antibody, srsf2.L antibody
- 背景
- SC35 belongs to a highly conserved SR splicing factor family. Members of this family have characteristic RNA-binding domains and serine/arginine-rich (SR) motifs. SR proteins are expressed in the nucleus and are essential pre-messenger RNA splicing factors. Nuclear pre-messenger RNA takes place in spliceosomes, multicomponent complexes consisting of five small nuclear ribonucleoprotein particles (U1, U2, U4, U5, U6) and other non-snRNP factors such as SC35. SC35 is necessary for an early step in spliceosome assembly and can also influence the selection of alternative splice sites. SC35 is identified as a 35 kDa protein in SDS/PAGE. Clone alphaSC35 has been shown to recognize SC35 in human, and rat cells. However, it should recognize SC35 from any species, as SC35 is conserved from Drosophila to man. Partially purified spliceosomes were used as immunogen.
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