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ROR1 抗体 (Extracellular)

ROR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H6 unconjugated
产品编号 ABIN966973
发货至: 中国
  • 抗原 See all ROR1 抗体
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    抗原表位
    • 13
    • 10
    • 10
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-406, Extracellular
    适用
    • 73
    • 29
    • 23
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 74
    • 3
    • 1
    小鼠
    克隆类型
    • 74
    • 4
    单克隆
    标记
    • 32
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ROR1 antibody is un-conjugated
    应用范围
    • 60
    • 31
    • 23
    • 20
    • 6
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    Ascitic fluid
    免疫原
    Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells
    克隆位点
    2H6
    亚型
    IgG1
    Top Product
    Discover our top product ROR1 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    别名
    ROR1 (ROR1 产品)
    别名
    NTRKR1 antibody, dJ537F10.1 antibody, 2810404D04Rik antibody, Ntrkr1 antibody, mRor1 antibody, RGD1559469 antibody, ROR1 antibody, fi34e02 antibody, si:dkey-209n16.1 antibody, wu:fi34e02 antibody, receptor tyrosine kinase like orphan receptor 1 antibody, receptor tyrosine kinase-like orphan receptor 1 antibody, ROR1 antibody, Ror1 antibody, ror1 antibody
    背景
    ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.
    Synonyms: ROR1
    分子量
    101kDa
    基因ID
    4919
    途径
    RTK signaling, WNT signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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