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PRTN3 抗体

PRTN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B4 unconjugated
产品编号 ABIN966909
发货至: 中国
  • 抗原 See all PRTN3 抗体
    PRTN3 (Proteinase 3 (PRTN3))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PRTN3 antibody is un-conjugated
    应用范围
    • 60
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    Western Blotting (WB), ELISA
    纯化方法
    Antibodies are purified by protein G affinity chromatography.
    免疫原
    Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
    克隆位点
    3B4
    亚型
    IgG2b
    Top Product
    Discover our top product PRTN3 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Clin, Aubin, Parent, Ronsky, Labelle: "Biomechanical modeling of brace design." in: Studies in health technology and informatics, Vol. 123, pp. 255-60, (2006) (PubMed).

    Abdgawad, Hellmark, Gunnarsson, Westman, Segelmark: "Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism." in: Clinical and experimental immunology, Vol. 145, Issue 1, pp. 63-70, (2006) (PubMed).

  • 抗原
    PRTN3 (Proteinase 3 (PRTN3))
    别名
    Proteinase 3 (PRTN3 产品)
    别名
    ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody
    背景
    Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
    Synonyms: PRTN3, ACPA, CANCA
    分子量
    28kDa
    基因ID
    5657
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