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PLAUR 抗体 (C-Term)

PLAUR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966859
发货至: 中国
  • 抗原 See all PLAUR 抗体
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    抗原表位
    • 16
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 64
    • 28
    • 27
    宿主
    • 58
    • 15
    • 4
    • 3
    克隆类型
    • 65
    • 15
    多克隆
    标记
    • 41
    • 8
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLAUR antibody is un-conjugated
    应用范围
    • 63
    • 31
    • 27
    • 20
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Urokinase plasminogen activator surface receptor (PLAUR) detection. Tested with WB, IHC-P in Human.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminal of human PLAUR.< br/>Immunogen was affinity purified.
    亚型
    IgG
    Top Product
    Discover our top product PLAUR Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Wang, Yang, Jamaluddin, Boyd: "The Kruppel-like KLF4 transcription factor, a novel regulator of urokinase receptor expression, drives synthesis of this binding site in colonic crypt luminal surface epithelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22674-83, (2004) (PubMed).

    Vagnarelli, Raimondi, Mazzieri, De Carli, Mignatti: "Assignment of the human urokinase receptor gene (PLAUR) to 19q13." in: Cytogenetics and cell genetics, Vol. 60, Issue 3-4, pp. 197-9, (1992) (PubMed).

  • 抗原
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    别名
    Urokinase plasminogen activator surface receptor(U-PAR/uPAR) (PLAUR 产品)
    别名
    Cd87 antibody, u-PAR antibody, uPAR antibody, CD87 antibody, U-PAR antibody, UPAR antibody, URKR antibody, Par antibody, Plaur3 antibody, uPAR-2 antibody, uPAR-3 antibody, PLAUR antibody, plasminogen activator, urokinase receptor antibody, Plaur antibody, PLAUR antibody
    背景
    PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13. 31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.
    途径
    Inositol Metabolic Process
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