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ErbB2/Her2 抗体

ErbB2/Her2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9B9D8 unconjugated
产品编号 ABIN966273
发货至: 中国
  • 抗原 See all ErbB2/Her2 抗体
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    适用
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    小鼠
    克隆类型
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    单克隆
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    This ErbB2/Her2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of HER-2 expressed in E. Coli.
    克隆位点
    9B9D8
    亚型
    IgG2b
    Top Product
    Discover our top product ErbB2/Her2 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Yamauchi, Stearns, Hayes: "When is a tumor marker ready for prime time? A case study of c-erbB-2 as a predictive factor in breast cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 19, Issue 8, pp. 2334-56, (2001) (PubMed).

    Ferrero-Poüs, Hacène, Bouchet, Le Doussal, Tubiana-Hulin, Spyratos: "Relationship between c-erbB-2 and other tumor characteristics in breast cancer prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 6, Issue 12, pp. 4745-54, (2001) (PubMed).

    Mehta, McDermott, Hieken, Marler, Patel, Wild, Das Gupta: "Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 16, Issue 7, pp. 2409-16, (1998) (PubMed).

  • 抗原
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    别名
    HER-2 (ErbB2/Her2 产品)
    别名
    CD340 antibody, HER-2 antibody, HER-2/neu antibody, HER2 antibody, MLN 19 antibody, NEU antibody, NGL antibody, TKR1 antibody, Erbb-2 antibody, Neu antibody, c-erbB2 antibody, c-neu antibody, mKIAA3023 antibody, wu:fv70f10 antibody, zgc:63601 antibody, erb2 antibody, erb-b2 receptor tyrosine kinase 2 antibody, ERBB2 antibody, Erbb2 antibody, erbb2 antibody
    背景
    The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis
    Synonyms: HER-2, C-erB-2, erbB-2
    基因ID
    2064
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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