(2 references)-
- 抗原 See all MAPK6 抗体
- MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAPK6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human ERK3 expressed in E. Coli.
- 克隆位点
- 4E8
- 亚型
- IgG1
- Top Product
- Discover our top product MAPK6 Primary Antibody
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anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 612-721) antibody
MAPK6 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 612-721) antibodyMAPK6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4-00E-08 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 1-316) antibodyMAPK6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (pSer189) antibodyMAPK6 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB5800 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 372-721) antibodyKO Validated MAPK6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (Center) antibodyMAPK6 适用: 人, 小鼠, Cow, 小鸡, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).
: "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5." in: Journal of cellular physiology, Vol. 217, Issue 3, pp. 778-88, (2008) (PubMed).
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: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).
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- 抗原
- MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
- 别名
- ERK3 (MAPK6 产品)
- 别名
- ERK3 antibody, HsT17250 antibody, PRKM6 antibody, p97MAPK antibody, 2610021I23Rik antibody, D130053K17Rik antibody, Erk3 antibody, Mapk4 antibody, Mapk63 antibody, Prkm4 antibody, Prkm6 antibody, ATMAPK6 antibody, ATMPK6 antibody, F18O19.10 antibody, MAP KINASE 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, SUSERK3 antibody, erk3 antibody, p97mapk antibody, si:ch211-235f12.1 antibody, mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, Mapk6 antibody, MPK6 antibody, mapk6 antibody
- 背景
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The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts
Synonyms: ERK3, PRKM6, p97MAPK, HsT17250, DKFZp686F03189, MAPK6 - 分子量
- 105kDa
- 基因ID
- 5596
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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