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MUC1 抗体 (DTRP (Asp-Thr-Arg-Pro))

MUC1 适用: 人 IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal B24-1 (GP1-4) unconjugated
产品编号 ABIN966067
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    抗原表位
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    DTRP (Asp-Thr-Arg-Pro)
    适用
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    宿主
    • 196
    • 86
    • 2
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    小鼠
    克隆类型
    • 175
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    单克隆
    标记
    • 144
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    This MUC1 antibody is un-conjugated
    应用范围
    • 140
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Concentrated.
    免疫原
    Human Milk Fat Globule Membranes
    克隆位点
    B24-1 (GP1-4)
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    Immunohistochemistry: (Paraffin/Frozen): 1:50.
    Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
    说明

    Cellular Localization: Cell Membrane, Cytoplasmic.
    Recommended Positive Control: Breast Carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/ml.
    缓冲液
    20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Hilkens, Ligtenberg, Vos, Litvinov: "Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).

    Hilkens, Buijs, Hilgers, Hageman, Calafat, Sonnenberg, van der Valk: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).

  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    EMA (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景
    Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
    分子量
    265-400 kDa
    基因ID
    4582
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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