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CTCF 抗体

CTCF 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 1D11 unconjugated
产品编号 ABIN965942
发货至: 中国
  • 抗原 See all CTCF 抗体
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    适用
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    人, 猴
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CTCF antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CTCF expressed in E. Coli.
    克隆位点
    1D11
    亚型
    IgG1
    Top Product
    Discover our top product CTCF Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Stedman, Kang, Lin, Kissil, Bartolomei, Lieberman: "Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).

  • 抗原
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    别名
    CTCF (CTCF 产品)
    别名
    im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
    背景
    This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.
    Tissue specificity: Ubiquitous. Absent in primary spermatocytes.
    Synonyms: CTCF
    分子量
    83kDa
    基因ID
    10664
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