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ATP6V0A4 抗体 (C-Term)

ATP6V0A4 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965622
发货至: 中国
  • 抗原 See all ATP6V0A4 抗体
    ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
    抗原表位
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 17
    • 2
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP6V0A4 antibody is un-conjugated
    应用范围
    • 14
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Human ATP6V0A4(ATPase, H+ transporting, lysosomal V0 subunit aisoform 4)
    Top Product
    Discover our top product ATP6V0A4 Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
    别名
    ATP6V0A4 (ATP6V0A4 产品)
    别名
    A4 antibody, ATP6N1B antibody, ATP6N2 antibody, RDRTA2 antibody, RTA1C antibody, RTADR antibody, STV1 antibody, VPH1 antibody, VPP2 antibody, Atp6n1b antibody, a4 antibody, ATPase H+ transporting V0 subunit a4 antibody, ATPase, H+ transporting, lysosomal V0 subunit A4 antibody, ATP6V0A4 antibody, Atp6v0a4 antibody
    背景
    ATP6V0A4(ATPase, H+ transporting, lysosomal V0 subunit aisoform 4) is a component of vacuolar ATPase(V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It contains the ATP catalytic site. The ATP6V0A4 protein is one of three 116 kD subunits family. This family consists of the 116kDa V-type ATPase (vacuolar H+)-ATPases) subunits, as well as V-type ATP synthase subunit i. The V-type ATPases family are proton pumps that acidify intracellular compartments in eukaryotic cells for example yeast central vacuoles, clathrin-coated and synaptic vesicles. They have important roles in membrane trafficking processes. The 116kDa subunit (subunit a) in the V-type ATPase is part of the V0 functional domain responsible for proton transport. The a subunit is a transmembrane glycoprotein with multiple putative transmembrane helices it has a hydrophilic amino terminal and a hydrophobic carboxy terminal. It has roles in proton transport and assembly of the V-type ATPase complex. This subunit is encoded by two homologous gene in yeast VPH1 and STV1
    途径
    Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport
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