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- 抗原 See all WWTR1 抗体
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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抗原表位
- AA 369-398, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWTR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects WWTR1 / TAZ (C-term).
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein A column followed by peptide affinity purification
- 免疫原
- KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human WWTR1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product WWTR1 Primary Antibody
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anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 1-230) antibody
WWTR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (N-Term) antibodyWWTR1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 201-300) antibodyWWTR1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal CL0371 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人, 小鼠, 大鼠 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (C-Term) antibodyWWTR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 296-330), (C-Term) antibodyWWTR1 适用: 人 WB 宿主: 兔 Polyclonal RB51589 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 296-330), (C-Term) antibodyWWTR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51590 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- 抗原
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- 别名
- WWTR1 / TAZ (WWTR1 产品)
- 别名
- WWTR1 antibody, TAZ antibody, 2310058J06Rik antibody, 2610021I22Rik antibody, C78399 antibody, Taz antibody, WW domain containing transcription regulator 1 L homeolog antibody, WW domain containing transcription regulator 1 antibody, wwtr1.L antibody, wwtr1 antibody, WWTR1 antibody, Wwtr1 antibody
- 背景
- Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.Synonyms: Transcriptional coactivator with PDZ-binding motif, WW domain-containing transcription regulator protein 1
- 基因ID
- 25937
- NCBI登录号
- NP_001161750
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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