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- 抗原 See all MOB1A (MOBKL1B) 抗体
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
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抗原表位
- AA 4-33, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MOB1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes Human MOBKL1B (N-term).
- 纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of Human MOBKL1B
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MOBKL1B Primary Antibody
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anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 2-216) antibody
MOBKL1B 适用: 人 ELISA, WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 1-216) antibodyMOBKL1B 适用: 人 ELISA, WB, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2D3D11 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 1-216) antibodyMOBKL1B 适用: 人 ELISA, WB, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3E7B2 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 188-216), (C-Term) antibodyMOBKL1B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19210 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (Internal Region) antibodyMOBKL1B 适用: 人, 小鼠, 猴 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 167-216) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (Internal Region) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 5-33), (N-Term) antibodyMOBKL1B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19209 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
- 别名
- MOBKL1B (MOBKL1B 产品)
- 别名
- mob1 antibody, mob4b antibody, MOB1A antibody, MOBK1B antibody, MOB1 antibody, mats1 antibody, mobk1b antibody, mobkl1b antibody, MOBKL1B antibody, wu:fv69d04 antibody, zgc:56189 antibody, C2orf6 antibody, MATS1 antibody, Mob4B antibody, 4022402H07Rik antibody, MOB4B antibody, Mobk1b antibody, Mobkl1b antibody, MOB kinase activator 1A L homeolog antibody, MOB kinase activator 1A antibody, MOB kinase activator 1A pseudogene antibody, mob1a.L antibody, MOB1A antibody, mob1a antibody, LOC712156 antibody, Mob1a antibody
- 背景
- Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.Synonyms: C2orf6, MOB4B, MOBK1B, Mob1 alpha, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, Protein Mob4B
- 分子量
- 25080 Da
- 基因ID
- 55233
- NCBI登录号
- NP_060691
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