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CPSF4 抗体 (Middle Region)

CPSF4 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951684
发货至: 中国
  • 抗原 See all CPSF4 抗体
    CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
    抗原表位
    • 12
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 102-132, Middle Region
    适用
    • 45
    • 14
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 3
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPSF4 antibody is un-conjugated
    应用范围
    • 45
    • 20
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human CPSF4 (Center).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 102~132 amino acids from the Central region of Human CPSF4. Genename: CPSF4
    亚型
    Ig Fraction
    Top Product
    Discover our top product CPSF4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
    别名
    CPSF4 (CPSF4 产品)
    别名
    cpsf30 antibody, nar antibody, neb1 antibody, 30kDa antibody, C79664 antibody, CPSF30 antibody, NAR antibody, NEB1 antibody, cleavage and polyadenylation specific factor 4 antibody, cleavage and polyadenylation specific factor 4, 30kDa antibody, cleavage and polyadenylation specific factor 4 S homeolog antibody, CPSF4 antibody, Cpsf4 antibody, LOC733099 antibody, LOC100360200 antibody, cpsf4.S antibody, cpsf4 antibody
    背景
    Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs.Synonyms: CPSF30, Cleavage and polyadenylation specificity factor 30 kDa subunit, Cleavage and polyadenylation specificity factor subunit 4, NAR, NEB1, NS1 effector domain-binding protein 1, No arches homolog
    分子量
    30255 Da
    基因ID
    10898
    NCBI登录号
    NP_001075028
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