TRIM 抗体 (Intracellular)
(1 reference)-
- 抗原 See all TRIM (TRAT1) 抗体
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
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抗原表位
- AA 29-186, Intracellular
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRIM antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- The antibody TRIM-04 recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
- 无交叉反应
- 小鼠
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Recombinant intracellular domain (aa 29-186) of human TRIM.
- 克隆位点
- TRIM-04
- 亚型
- IgG2a
- Top Product
- Discover our top product TRAT1 Primary Antibody
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anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186), (Intracellular) antibody (PE)
TRAT1 适用: 人 FACS 宿主: 小鼠 Monoclonal TRIM-04 PE
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186) antibodyTRAT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186) antibodyTRAT1 适用: 人, 小鼠 WB, FACS, IF 宿主: 小鼠 Monoclonal TRIM-4 unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 98-127) antibodyTRAT1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB30370 unconjugated
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- 应用备注
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Flow cytometry: Recommended dilution: 1-4 μg/mL, intracellular staining.
Western blotting: Non-reducing conditions. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain." in: The Journal of experimental medicine, Vol. 193, Issue 11, pp. 1269-84, (2001) (PubMed).
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: "The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain." in: The Journal of experimental medicine, Vol. 193, Issue 11, pp. 1269-84, (2001) (PubMed).
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- 抗原
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
- 别名
- TRIM (TRAT1 产品)
- 别名
- TCRIM antibody, TRIM antibody, C030046M14Rik antibody, Tcrim antibody, Trim antibody, T cell receptor associated transmembrane adaptor 1 antibody, T-cell receptor associated transmembrane adaptor 1 antibody, TRAT1 antibody, Trat1 antibody
- 背景
- T cell receptor associated transmembrane adaptor 1,TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.,TRAT, TCRIM
- 基因ID
- 50852
- UniProt
- Q6PIZ9
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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