电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CD34 抗体

CD34 适用: 人 FACS, WB, IHC (p), ICC 宿主: 小鼠 Monoclonal 4H11[APG] unconjugated
产品编号 ABIN94077
发货至: 中国
  • 抗原 See all CD34 抗体
    CD34
    适用
    • 300
    • 105
    • 104
    • 33
    • 19
    • 17
    • 17
    • 17
    • 16
    • 16
    • 9
    • 6
    • 6
    • 1
    • 1
    宿主
    • 169
    • 145
    • 17
    • 4
    小鼠
    克隆类型
    • 216
    • 116
    • 2
    单克隆
    标记
    • 127
    • 28
    • 24
    • 21
    • 14
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD34 antibody is un-conjugated
    应用范围
    • 233
    • 202
    • 90
    • 64
    • 58
    • 52
    • 39
    • 37
    • 30
    • 28
    • 24
    • 19
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    特异性
    The mouse monoclonal antibody 4H11[APG] reacts with extracellular class III epitope on CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of class III antibodies BIRMA K3 and 8G12 on KG1a cell line.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia.
    克隆位点
    4H11[APG]
    亚型
    IgG1
    Top Product
    Discover our top product CD34 Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: Kg-1a, TF-1 cells, non-reducing conditions.
    Flow cytometry: Recommended dilution: 2 μg/mL.
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: placenta endothelium.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Elknerová, Lacinová, Soucek, Marinov, Stöckbauer: "Growth inhibitory effect of the antibody to hematopoietic stem cell antigen CD34 in leukemic cell lines." in: Neoplasma, Vol. 54, Issue 4, pp. 311-20, (2007) (PubMed).

  • 抗原
    CD34
    别名
    CD34 (CD34 产品)
    别名
    AU040960 antibody, CD34 molecule antibody, CD34 antigen antibody, CD34 antibody, Cd34 antibody
    背景
    CD34 Molecule,CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
    基因ID
    947
    UniProt
    P28906
You are here:
客服