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CD33 抗体

CD33 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HIM3-4 unconjugated
产品编号 ABIN94072
发货至: 中国
  • 抗原 See all CD33 抗体
    CD33
    适用
    • 163
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    人, Non-Human Primate
    宿主
    • 95
    • 74
    小鼠
    克隆类型
    • 90
    • 78
    • 1
    单克隆
    标记
    • 58
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    This CD33 antibody is un-conjugated
    应用范围
    • 104
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    Flow Cytometry (FACS)
    特异性
    The antibody HIM3-4 reacts with an extracellular epitope of CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    NFMY-9s human cell line
    克隆位点
    HIM3-4
    亚型
    IgG1
    Top Product
    Discover our top product CD33 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • McCormack, Muji?, Osdal, Bruserud, Gjertsen: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." in: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).

  • 抗原
    CD33
    别名
    CD33 (CD33 产品)
    别名
    SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody
    背景
    CD33 Molecule,CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.,SIGLEC3, p67
    基因ID
    945
    UniProt
    P20138
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