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CD2 抗体 (Biotin)

CD2 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-65 Biotin
产品编号 ABIN94022
发货至: 中国
  • 抗原 See all CD2 抗体
    CD2
    适用
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    宿主
    • 131
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    • 2
    小鼠
    克隆类型
    • 150
    • 43
    • 2
    单克隆
    标记
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    This CD2 antibody is conjugated to Biotin
    应用范围
    • 140
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    免疫原
    Human peripheral T cells.
    克隆位点
    MEM-65
    亚型
    IgG1
    Top Product
    Discover our top product CD2 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    说明

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Espagnolle, Depoil, Zaru, Demeur, Champagne, Guiraud, Valitutti: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).

    Drbal, Hilgert, Cebecauer, Angelisová, Horejsí: "New monoclonal antibodies to human leucocyte surface molecule CD2." in: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).

  • 抗原
    CD2
    别名
    CD2 (CD2 产品)
    别名
    CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
    背景
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
    基因ID
    914
    UniProt
    P06729
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