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MGA 抗体

适用: 人 DB 宿主: 小鼠 Monoclonal MGA6A4H5 unconjugated
产品编号 ABIN930939
发货至: 中国
  • 抗原
    MGA
    适用
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 5
    小鼠
    克隆类型
    • 5
    单克隆
    标记
    • 5
    非结合性
    应用范围
    • 2
    • 2
    • 1
    Dot Blot (DB)
    交叉反应
    交叉反应 (详细)
    Other species not studied.
    纯化方法
    Protein G affinity chromatography
    免疫原
    MGA antibody was raised in mouse using recombinant Max Gene Associated
    克隆位点
    MGA6A4H5
    亚型
    IgG1
  • 应用备注
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    MGA antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原
    MGA
    背景
    This gene functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. Synonyms: Monoclonal MGA antibody, Anti-MGA antibody, MAX dimerization protein 5 antibody, KIAA0518 antibody, MAD5 antibody, MXD5 antibody, FLJ12634 antibody.
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