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USP20 抗体 (Middle Region)

USP20 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN929196
发货至: 中国
  • 抗原 See all USP20 抗体
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 42
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    • 4
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 4
    • 4
    This USP20 antibody is un-conjugated
    应用范围
    • 30
    • 26
    • 17
    • 4
    • 4
    Western Blotting (WB)
    纯化方法
    Purified
    免疫原
    USP20 antibody was raised in rabbit using the middle region of USP20 as the immunogen
    Top Product
    Discover our top product USP20 Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    别名
    USP20 (USP20 产品)
    别名
    USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody
    背景
    USP20 is a deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling.USP20 acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). USP20 plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Synonyms: Polyclonal USP20 antibody, Anti-USP20 antibody, ubiquitin specific peptidase 20 antibody, KIAA1003 antibody, LSFR3A antibody, VDU2 antibody.
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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