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TUSC2 抗体 (AA 31-100) (Alexa Fluor 555)

TUSC2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN919019
发货至: 中国
  • 抗原 See all TUSC2 抗体
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    抗原表位
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-100
    适用
    • 29
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 27
    • 2
    • 1
    克隆类型
    • 29
    • 1
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TUSC2 antibody is conjugated to Alexa Fluor 555
    应用范围
    • 27
    • 15
    • 12
    • 12
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TUSC2
    亚型
    IgG
    Top Product
    Discover our top product TUSC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    别名
    TUSC2 (TUSC2 产品)
    别名
    C3orf11 antibody, FUS1 antibody, PAP antibody, PDAP2 antibody, TUSC2 antibody, 1190001E22Rik antibody, AA407686 antibody, Fus1 antibody, Lgcc antibody, Pdap2 antibody, zgc:92701 antibody, zgc:153746 antibody, tumor suppressor candidate 2 antibody, tumor suppressor candidate 2 L homeolog antibody, tumor suppressor candidate 2b antibody, tumor suppressor candidate 2a antibody, TUSC2 antibody, tusc2.L antibody, Tusc2 antibody, tusc2b antibody, tusc2a antibody
    背景

    Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.

    Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.

    基因ID
    11334
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