SLC22A17 抗体 (AA 475-538) (AbBy Fluor® 350)
Quick Overview for SLC22A17 抗体 (AA 475-538) (AbBy Fluor® 350) (ABIN908243)
抗原
See all SLC22A17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 475-538
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLC22A17
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SLC22A17 (Solute Carrier Family 22 (Organic Cation Transporter), Member 17 (SLC22A17))
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别名
- Slc22A17
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背景
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Synonyms: BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3, Solute carrier family 22 member 17, 24p3 receptor, Brain-type organic cation transporter, Lipocalin-2 receptor, Neutrophil gelatinase-associated lipocalin receptor, SLC22A17
Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).
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基因ID
- 51310
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UniProt
- Q8WUG5
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途径
- Transition Metal Ion Homeostasis
抗原
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