Hemagglutinin 抗体 (AA 151-250) (Alexa Fluor 555)
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- 抗原 See all Hemagglutinin (HA) 抗体
- Hemagglutinin (HA)
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抗原表位
- AA 151-250
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适用
- Influenza A Virus H1N1, Virus
- Virus Strain
- A/California/04/2009
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Hemagglutinin antibody is conjugated to Alexa Fluor 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- Virus
- 交叉反应 (详细)
- Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)
- 产品特性
- Antibody is specific for: Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from Influenza A Virus Hemagglutinin (strain swl A/California/04/2009 H1N1)
- 亚型
- IgG
- Top Product
- Discover our top product HA Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Hemagglutinin (HA)
- Abstract
- HA 产品
- 别名
- hemagglutinin antibody, Hemagglutinin antibody, HA antibody, HA antibody, ha antibody
- 物质类
- Influenza Protein
- 背景
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Synonyms: HA, Hemagglutinin, Influenza A Virus (strain swl A/California/04/2009 H1N1)
Background: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Influenza A Virus (strain swl A/California/04/2009 H1N1)
- UniProt
- C3W5S1
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