CLEC5A 抗体 (AA 101-190) (AbBy Fluor® 488)
Quick Overview for CLEC5A 抗体 (AA 101-190) (AbBy Fluor® 488) (ABIN891258)
抗原
See all CLEC5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-190
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse CLEC5A
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
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别名
- CLEC5A
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背景
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Synonyms: Mdl1, Ly100, MDL-1, Clecsf5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, Clec5a
Background: Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.
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基因ID
- 23845
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UniProt
- Q9R007
抗原
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