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RBPJ 抗体 (AA 101-200)

RBPJ 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872972
发货至: 中国
  • 抗原 See all RBPJ 抗体
    RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 76
    • 30
    • 15
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 70
    • 3
    • 2
    • 2
    克隆类型
    • 63
    • 14
    多克隆
    标记
    • 35
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBPJ antibody is un-conjugated
    应用范围
    • 57
    • 28
    • 22
    • 12
    • 12
    • 10
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RBPJK
    亚型
    IgG
    Top Product
    Discover our top product RBPJ Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
    别名
    RBPJK (RBPJ 产品)
    别名
    AOS3 antibody, CBF1 antibody, IGKJRB antibody, IGKJRB1 antibody, KBF2 antibody, RBP-J antibody, RBPJK antibody, RBPSUH antibody, SUH antibody, csl antibody, AI843960 antibody, Igkjrb antibody, Igkrsbp antibody, RBP-J kappa antibody, RBPjk antibody, Rbpsuh antibody, Su(H) antibody, XSu(H) antibody, xsu(h)1 antibody, Su(H)1 antibody, Su(h)A antibody, ik:tdsubc_1e8 antibody, rbpj antibody, rbpsuh antibody, xx:tdsubc_1e8 antibody, Su(H)2 antibody, su(h)B antibody, recombination signal binding protein for immunoglobulin kappa J region antibody, recombination signal binding protein for immunoglobulin kappa J region S homeolog antibody, recombination signal binding protein for immunoglobulin kappa J region a antibody, recombination signal binding protein for immunoglobulin kappa J region b antibody, RBPJ antibody, Rbpj antibody, rbpj.S antibody, rbpja antibody, rbpjb antibody
    背景

    Synonyms: SUH, csl, AOS3, CBF1, KBF2, RBP-J, RBPJK, IGKJRB, RBPSUH, IGKJRB1, Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-JK, Renal carcinoma antigen NY-REN-30, RBPJ

    Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.

    基因ID
    3516
    UniProt
    Q06330
    途径
    Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
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