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DNASE2 抗体 (AA 25-90)

DNASE2 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN872658
发货至: 中国
  • 抗原 See all DNASE2 抗体
    DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
    抗原表位
    • 14
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 25-90
    适用
    • 33
    • 20
    • 2
    人, 小鼠
    宿主
    • 31
    • 3
    克隆类型
    • 34
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNASE2 antibody is un-conjugated
    应用范围
    • 15
    • 15
    • 12
    • 12
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DNase II alpha
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

  • 抗原
    DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
    别名
    DNase 2 alpha (DNASE2 产品)
    别名
    CG7780 antibody, DNase antibody, DNase 1 antibody, DNase-1 antibody, DNase1 antibody, Dmel\\CG7780 antibody, dDNase II antibody, dnase2 antibody, MGC80103 antibody, DNASE2 antibody, LOC733868 antibody, fa92d01 antibody, wu:fa56d08 antibody, wu:fa92d01 antibody, DDBDRAFT_0188966 antibody, DDBDRAFT_0252883 antibody, DDB_0188966 antibody, DDB_0252883 antibody, Dnase2 antibody, DNASE2A antibody, DNL antibody, DNL2 antibody, Dnase2a antibody, Deoxyribonuclease II antibody, deoxyribonuclease II, lysosomal L homeolog antibody, deoxyribonuclease 2, lysosomal antibody, deoxyribonuclease II, lysosomal antibody, deoxyribonuclease II antibody, deoxyribonuclease II alpha antibody, DNaseII antibody, dnase2.L antibody, DNASE2 antibody, dnase2 antibody, Dnase2a antibody, Dnase2 antibody
    背景

    Synonyms: DNL, DNL2, DNASE2A, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II, R31240_2, DNASE2

    Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

    基因ID
    1777
    UniProt
    O00115
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