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- 抗原 See all SLC39A1 抗体
- SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC39A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Zinc transporter ZIP1 / SLC39A1 at N-term.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid peptide near the amino terminus of human ZIP1
- Top Product
- Discover our top product SLC39A1 Primary Antibody
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anti-Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1) (AA 5-20), (Extracellular), (N-Term) antibody
SLC39A1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1) (AA 41-317) antibodySLC39A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1) (Internal Region) antibodySLC39A1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1) (AA 1-227) antibodySLC39A1 适用: Saccharomyces cerevisiae ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))
- 别名
- Zinc Transporter ZIP1 / SLC39A1 (SLC39A1 产品)
- 别名
- cb629 antibody, DrZIP1 antibody, sb:cb629 antibody, zgc:111852 antibody, frzip1p antibody, zip1 antibody, zirtl antibody, ZIP1 antibody, ZIRTL antibody, Zip1 antibody, Zirtl antibody, solute carrier family 39 (zinc transporter), member 1 antibody, solute carrier family 39 member 1 antibody, solute carrier family 39 member 1 L homeolog antibody, slc39a1 antibody, Slc39a1 antibody, SLC39A1 antibody, slc39a1.L antibody
- 背景
- ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappaB, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.Synonyms: IRT1, Solute carrier family 39 member 1, ZIP-1, ZIP1, ZIRTL, Zinc-iron-regulated transporter-like, Zrt- and Irt-like protein 1
- 基因ID
- 27173
- NCBI登录号
- NP_055252
- UniProt
- Q9NY26
- 途径
- Autophagy
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