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SLC5A8 抗体 (AA 301-336) (FITC)

SLC5A8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal FITC
产品编号 ABIN762528
发货至: 中国
  • 抗原 See all SLC5A8 抗体
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    抗原表位
    • 14
    • 11
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-336
    适用
    • 33
    • 27
    • 23
    • 5
    • 5
    • 5
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    克隆类型
    • 44
    多克隆
    标记
    • 12
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A8 antibody is conjugated to FITC
    应用范围
    • 39
    • 21
    • 3
    • 2
    • 1
    Western Blotting (WB)
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLC5A8
    亚型
    IgG
    Top Product
    Discover our top product SLC5A8 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    别名
    Slc5a8 (SLC5A8 产品)
    别名
    Ait antibody, SMCT antibody, SMCT1 antibody, AIT antibody, RGD1564146 antibody, solute carrier family 5 (iodide transporter), member 8 antibody, solute carrier family 5 member 8 antibody, Slc5a8 antibody, SLC5A8 antibody
    背景

    Synonyms: AIT, SMCT, SMCT1, Sodium-coupled monocarboxylate transporter 1, Apical iodide transporter, Electrogenic sodium monocarboxylate cotransporter, Sodium iodide-related cotransporter, Solute carrier family 5 member 8, SLC5A8

    Background: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.

    基因ID
    160728
    UniProt
    Q8N695
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