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MFSD2A 抗体 (AA 331-430) (HRP)

MFSD2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN762035
发货至: 中国
  • 抗原 See all MFSD2A 抗体
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    抗原表位
    • 15
    • 2
    • 2
    AA 331-430
    适用
    • 19
    • 18
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MFSD2A antibody is conjugated to HRP
    应用范围
    • 19
    • 14
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MFSD2A
    亚型
    IgG
    Top Product
    Discover our top product MFSD2A Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))
    别名
    MFSD2A (MFSD2A 产品)
    别名
    1700018O18Rik antibody, Mfsd2 antibody, RGD1310174 antibody, MFSD2 antibody, NLS1-A antibody, Sodium-dependent LPC symporter 1-A antibody, mfsd2a antibody, zgc:101615 antibody, mfsd2 antibody, NLS1-B antibody, Sodium-dependent LPC symporter 1-B antibody, mfsd2b antibody, zgc:101069 antibody, major facilitator superfamily domain containing 2A antibody, major facilitator superfamily domain containing 2aa antibody, major facilitator superfamily domain containing 2A L homeolog antibody, major facilitator superfamily domain containing 2ab antibody, MFSD2A antibody, mfsd2a antibody, Mfsd2a antibody, mfsd2aa antibody, mfsd2a.L antibody, mfsd2ab antibody
    背景

    Synonyms: NLS1, MFSD2, Sodium-dependent lysophosphatidylcholine symporter 1, Sodium-dependent LPC symporter 1, Major facilitator superfamily domain-containing protein 2A, MFSD2A, HMFN0656, PP9177, UNQ300/PRO341

    Background: Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732).

    基因ID
    84879
    UniProt
    Q8NA29
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