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STRADA 抗体 (AA 1-100) (Cy5.5)

This anti-STRADA antibody is a 兔 多克隆 antibody detecting STRADA in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN751593
发货至: 中国

Quick Overview for STRADA 抗体 (AA 1-100) (Cy5.5) (ABIN751593)

抗原

See all STRADA 抗体
STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

适用

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  • 1
  • 1
小鼠

宿主

  • 60
  • 3

克隆类型

  • 61
  • 2
多克隆

标记

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  • 5
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  • 2
  • 1
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  • 1
  • 1
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  • 1
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This STRADA antibody is conjugated to Cy5.5

应用范围

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  • 33
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  • 3
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  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
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    • 2
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    • 1
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    • 1
    AA 1-100

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LYK5

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

    别名

    LYK5

    背景

    Synonyms: Serologically defined breast cancer antigen NY BR 96, STRAD alpha, Protein kinase LYK5, STE20 related adapter protein, STRAD, STRAA_HUMAN.

    Background: Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.

    基因ID

    92335

    途径

    AMPK Signaling
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