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Histone 3 抗体 (AA 71-136)

H3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN739109
发货至: 中国
  • 抗原 See all Histone 3 (H3) 抗体
    Histone 3 (H3)
    抗原表位
    • 60
    • 47
    • 45
    • 42
    • 42
    • 37
    • 36
    • 35
    • 35
    • 35
    • 34
    • 31
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    AA 71-136
    适用
    • 1402
    • 940
    • 860
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 29
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 1219
    • 244
    • 8
    • 4
    克隆类型
    • 1120
    • 354
    • 1
    多克隆
    标记
    • 824
    • 81
    • 63
    • 63
    • 63
    • 62
    • 62
    • 62
    • 37
    • 33
    • 23
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 2
    • 1
    This Histone 3 antibody is un-conjugated
    应用范围
    • 1061
    • 410
    • 382
    • 316
    • 254
    • 187
    • 180
    • 180
    • 162
    • 161
    • 141
    • 127
    • 118
    • 47
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Cow,Pig,Rabbit,Drosophila
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Histone H3
    亚型
    IgG
    Top Product
    Discover our top product H3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Si, Meng, Gao, Hui, Li, Liu, Yang: "Linagliptin protects rat carotid artery from balloon injury and activates the NRF2 antioxidant pathway." in: Experimental animals, Vol. 68, Issue 1, pp. 81-90, (2019) (PubMed).

    Zhang, Zhang, Li, Wang, Gu, Feng, Wei, Peng, Zhang, Su, Wang, Li, Yang, Wong, Yang, Ma: "Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

    Joy, Gau, Castellucci, Prywes, Roy: "The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms." in: The Journal of biological chemistry, Vol. 292, Issue 28, pp. 11777-11791, (2017) (PubMed).

    Yang, Liu, Jiang, Wang, Zhang: "Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model." in: Frontiers in pharmacology, Vol. 8, pp. 44, (2017) (PubMed).

    Shen, Wu, Liu, Zhao, Zhao: "Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors." in: Life sciences, Vol. 170, pp. 25-32, (2016) (PubMed).

    Qian, Zhang, Hu, Xu, Chen, Hu, Zhao, Liu: "Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status." in: Biomaterials, Vol. 70, pp. 12-22, (2015) (PubMed).

    Duan, Liu, Liang, Yang, Xia, Wang, Chen, Yu: "Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 863-74, (2014) (PubMed).

    Tang, Chen, Liang, Rong, Yao, Yang, Wu: "Selective antegrade cerebral perfusion attenuating the TLR4/NF-?B pathway during deep hypothermia circulatory arrest in a pig model." in: Cardiology, Vol. 128, Issue 3, pp. 243-50, (2014) (PubMed).

    Wang, Ma, Su: "NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells." in: Biological trace element research, Vol. 153, Issue 1-3, pp. 403-10, (2013) (PubMed).

    Liu, Ji, Zhang, Tong, Pan, Liu, Zhang, Huang, Su, Willard, Zheng: "Nonenzymatic glycation of high-density lipoprotein impairs its anti-inflammatory effects in innate immunity." in: Diabetes/metabolism research and reviews, Vol. 28, Issue 2, pp. 186-95, (2012) (PubMed).

    Zhou, Zhou, Wang, Mu, Wu, Guo, Zhang, Wu: "Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro." in: Acta pharmacologica Sinica, Vol. 33, Issue 1, pp. 120-6, (2012) (PubMed).

  • 抗原
    Histone 3 (H3)
    别名
    Histone H3 (H3 产品)
    别名
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    背景

    Synonyms: Histone H3, H3.1, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FA, H3FL, H3FC, H3FB, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, H3.2, HIST2H3A, HIST2H3C, HIST2H3D, H3F2, H3FM, H3.3, H3F3A, H3F3B, H3.3A, H3.3B, H3F3, PP781, H3.3C, H3F3C, H3.5, H3.1t, HIST3H3, H3FT

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    基因ID
    3020
    UniProt
    P84243
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