beta Catenin 抗体 (AA 661-781)
(8 references)-
- 抗原 See all beta Catenin (CATNB) 抗体
- beta Catenin (CATNB) (Catenin, beta (CATNB))
-
抗原表位
- AA 661-781
-
适用
- 人, 小鼠, 大鼠, Pig, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This beta Catenin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, Pig, 大鼠, 斑马鱼
- 预测反应
- Cow,Sheep,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Beta catenin
- 亚型
- IgG
- Top Product
- Discover our top product CATNB Primary Antibody
-
anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 非洲爪蟾 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Pig, 兔, 绵羊, 猴, Hamster, Avian, Cat, 驴, 山羊, 豚鼠, 马 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C901 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 4A3H3 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB 适用: 人, 小鼠, Hamster WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) (AA 764-781) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "Suppression of Wnt5a, but not Wnts, relieves chronic post-thoracotomy pain via anti-inflammatory modulation in rats." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 474-480, (2017) (PubMed).
: "Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." in: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).
: "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." in: Journal of neurosurgery, pp. 1-9, (2016) (PubMed).
: "Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss." in: PeerJ, Vol. 4, pp. e2624, (2016) (PubMed).
: "BAMBI Promotes C2C12 Myogenic Differentiation by Enhancing Wnt/?-Catenin Signaling." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 17734-45, (2015) (PubMed).
: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, (2015) (PubMed).
: "Ubiquitin E3 ligase MARCH7 promotes ovarian tumor growth." in: Oncotarget, Vol. 6, Issue 14, pp. 12174-87, (2015) (PubMed).
: "Expression and Clinical Significance of Von Hippel-Lindau Downstream Genes: Jade-1 and β-Catenin Related to Renal Cell Carcinoma." in: Urology, (2012) (PubMed).
-
: "Suppression of Wnt5a, but not Wnts, relieves chronic post-thoracotomy pain via anti-inflammatory modulation in rats." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 474-480, (2017) (PubMed).
-
- 抗原
- beta Catenin (CATNB) (Catenin, beta (CATNB))
- 别名
- Beta catenin (CATNB 产品)
- 别名
- Bfc antibody, Catnb antibody, Mesc antibody, CTNNB antibody, MRD19 antibody, armadillo antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, beta-catenin antibody, ctnnb1 antibody, CHBCAT antibody, catenin (cadherin associated protein), beta 1 antibody, catenin beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 L homeolog antibody, Ctnnb1 antibody, CTNNB1 antibody, ctnnb1 antibody, ctnnb1.L antibody
- 背景
-
Synonyms: CTNNB, MRD19, armadillo, Catenin beta-1, Beta-catenin, CTNNB1, OK/SW-cl.35, PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
- 基因ID
- 1499
- UniProt
- P35222
- 途径
- Peptide Hormone Metabolism
-
