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CCL2 抗体 (AA 61-148)

CCL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN737676
发货至: 中国
  • 抗原 See all CCL2 抗体
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    抗原表位
    • 24
    • 15
    • 13
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 61-148
    适用
    • 98
    • 60
    • 58
    • 18
    • 18
    • 18
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 118
    • 56
    • 8
    • 7
    • 3
    • 2
    • 2
    克隆类型
    • 134
    • 62
    多克隆
    标记
    • 109
    • 33
    • 14
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CCL2 antibody is un-conjugated
    应用范围
    • 137
    • 68
    • 56
    • 27
    • 26
    • 24
    • 24
    • 18
    • 14
    • 13
    • 13
    • 12
    • 12
    • 11
    • 11
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from rat MCP-1
    亚型
    IgG
    Top Product
    Discover our top product CCL2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Li, Fang, Tian, Wang, Ao, Hou, Tong, Fan, Bai: "Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4455-4462, (2018) (PubMed).

    Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." in: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).

    Kuracha, Thomas, Loggie, Govindarajan: "Patient-derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment." in: Cancer medicine, Vol. 5, Issue 4, pp. 711-9, (2016) (PubMed).

    Jeong, Lee, Kim, Yang, Sung, Seong: "Irradiation-induced localization of IL-12-expressing mesenchymal stem cells to enhance the curative effect in murine metastatic hepatoma." in: International journal of cancer. Journal international du cancer, Vol. 137, Issue 3, pp. 721-30, (2015) (PubMed).

    Guo, Feng, Yao, Sun, Zhu: "Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy." in: BMC nephrology, Vol. 15, pp. 110, (2014) (PubMed).

    Iwasa, Arakaki, Honma, Ushio, Yamada, Kondo, Kurosawa, Kujiraoka, Tsunematsu, Kudo, Tanaka, Yoshimura, Harada, Hayashi, Ishimaru: "Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages." in: The American journal of pathology, Vol. 185, Issue 1, pp. 151-61, (2014) (PubMed).

    Su, Zhou, Wang, Yang, Li, Yu, Li: "The PPARβ/δ agonist GW501516 attenuates peritonitis in peritoneal fibrosis via inhibition of TAK1-NFκB pathway in rats." in: Inflammation, Vol. 37, Issue 3, pp. 729-37, (2014) (PubMed).

    Guo, Zhang, Li, Xu: "Effect of telmisartan on the expression of adiponectin receptors and nicotinamide adenine dinucleotide phosphate oxidase in the heart and aorta in type 2 diabetic rats." in: Cardiovascular diabetology, Vol. 11, pp. 94, (2012) (PubMed).

  • 抗原
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    别名
    MCP1 (CCL2 产品)
    别名
    GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
    背景

    Synonyms: MCP-1, Scya2, Sigje, C-C motif chemokine 2, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Small-inducible cytokine A2, Ccl2, Je, Mcp1

    Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer, in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.

    基因ID
    24770
    UniProt
    P14844
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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