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NeuN 抗体 (AA 51-150)

RBFOX3 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN732068
发货至: 中国
  • 抗原 See all NeuN (RBFOX3) 抗体
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 52
    • 43
    • 37
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔
    宿主
    • 41
    • 15
    • 2
    克隆类型
    • 31
    • 27
    多克隆
    标记
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NeuN antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 18
    • 14
    • 13
    • 12
    • 11
    • 11
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 兔, 大鼠
    预测反应
    Dog,Cow,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NeuN
    亚型
    IgG
    Top Product
    Discover our top product RBFOX3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Kopec, Rivera, Lacagnina, Hanamsagar, Bilbo: "Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue." in: Journal of neuroscience methods, Vol. 280, pp. 64-76, (2017) (PubMed).

    Wang, Tian, Wang, Wei, Wu, Wang, Wang, Yang, Ji, Li: "Anti-inflammatory and retinal protective effects of capsaicin on ischaemia-induced injuries through the release of endogenous somatostatin." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 7, pp. 803-814, (2017) (PubMed).

    Ridder, Sevko, Heide, Dams, Rupp, Macas, Starmann, Tjwa, Plate, Sültmann, Altevogt, Umansky, Momma: "Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment." in: Oncoimmunology, Vol. 4, Issue 6, pp. e1008371, (2015) (PubMed).

    Fontes, Ramsey, Polk, Koop, Denisova, Belousov: "Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125395, (2015) (PubMed).

    Hu, Lin, Zhu, Li, Chen: "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. [Corrected]." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3998, (2015) (PubMed).

    Guo, Zhang, Xu, Zhi, Han, Zhou, Liu, Lin, Zhang: "Bone marrow-derived, neural-like cells have the characteristics of neurons to protect the peripheral nerve in microenvironment." in: Stem cells international, Vol. 2015, pp. 941625, (2015) (PubMed).

    Zhao, Dumanis, Tamboli, Rodriguez, Jo Ladu, Moussa, William Rebeck: "Human APOE genotype affects intraneuronal A?1-42 accumulation in a lentiviral gene transfer model." in: Human molecular genetics, Vol. 23, Issue 5, pp. 1365-75, (2014) (PubMed).

    Zhao, Zhang, Davis, Rebeck: "Aging reduces glial uptake and promotes extracellular accumulation of A? from a lentiviral vector." in: Frontiers in aging neuroscience, Vol. 6, pp. 210, (2014) (PubMed).

    Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

    Li, Liang, Guan, Fan, Chi, Yang: "Regular treadmill running improves spatial learning and memory performance in young mice through increased hippocampal neurogenesis and decreased stress." in: Brain research, Vol. 1531, pp. 1-8, (2013) (PubMed).

    Wei, Chen, Chen, Lai, Liu, Deng, Zhou, Zhang, Li, Lii, Liu, Wang, Nie: "β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice." in: Journal of Alzheimer's disease : JAD, Vol. 33, Issue 3, pp. 863-80, (2013) (PubMed).

    Zhao, Zhang, Wang, Chen, Ji, Zhang: "(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death." in: Neurochemistry international, Vol. 60, Issue 2, pp. 134-44, (2012) (PubMed).

    Jiang, Fu, Tian, Zhu, Hou: "Curculigoside A attenuates experimental cerebral ischemia injury in vitro and vivo." in: Neuroscience, Vol. 192, pp. 572-9, (2011) (PubMed).

    Jiang, Tian, Fu, Zhu, Hou: "Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury." in: European journal of pharmacology, Vol. 640, Issue 1-3, pp. 75-81, (2010) (PubMed).

  • 抗原
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    别名
    FOX3/NeuN (RBFOX3 产品)
    别名
    FOX-3 antibody, FOX3 antibody, HRNBP3 antibody, NEUN antibody, Fox-3 antibody, Hrnbp3 antibody, NeuN antibody, Neuna60 antibody, Neun antibody, RGD1560070 antibody, RNA binding fox-1 homolog 3 antibody, RNA binding protein, fox-1 homolog (C. elegans) 3 antibody, RNA binding protein, fox-1 homolog 3 antibody, RBFOX3 antibody, Rbfox3 antibody
    背景

    Synonyms: FOX3, NEUN, FOX-3, HRNBP3, RNA binding protein fox-1 homolog 3, Fox-1 homolog C, RBFOX3

    Background: Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

    基因ID
    146713
    UniProt
    A6NFN3
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