Cadherin 5 抗体 (CDH5) (AA 621-660)

Details for Product anti-CDH5 Antibody No. ABIN729343, 供应商: Log in to see
抗原
  • 7B4
  • AA408225
  • Cd144
  • VE-Cad
  • VECD
  • VEcad
  • Vec
  • wu:fc88a07
  • CD144
  • cadherin-5
  • cadherin 5
  • CDH5
  • Cdh5
  • cdh5
抗原表位
AA 621-660
21
18
15
12
8
6
6
6
6
6
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
适用
人, 小鼠, 大鼠
247
163
51
5
3
2
2
2
1
1
1
宿主

153
123
74
3
克隆类型
多克隆
标记
This Cadherin 5 antibody is un-conjugated
24
18
16
14
13
6
6
6
5
4
4
4
4
4
4
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
应用范围
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
205
169
123
100
43
39
38
15
13
12
12
11
10
10
7
7
6
6
3
3
3
3
2
2
1
1
1
选项
Supplier
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Supplier Product No.
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免疫原 KLH conjugated synthetic peptide derived from mouse vascular endothelial cadherin
亚型 IgG
纯化方法 Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others Cadherin 5 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 VE Cadherin (CDH5 Antibody 摘要)
背景

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Subcellular location: Cytoplasm

Synonyms: 7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA48225, Cadherin-5, Vascular endothelial cadherin, VE-cadherin, Cdh5

基因ID 12562
UniProt P55284
途径 Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
应用备注 WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20°C
有效期 12 months
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-CD144/V...
Immunofluorescence (IF) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Images provided by Science Direct, badge number 029590: Formalin-fixed and frozen-OCT...
Western Blotting (WB) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) A549 lyates probed with Rabbit Anti-VE Cadherin Polyclonal Antibody, Unconjugated at...
Western Blotting (WB) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Mouse heart lysates probed with VE Cadherin Polyclonal Antibody, unconjugated at 1:3...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Image provided by One World Lab validation program. HEK293 cells probed with Rabbit A...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cadherin 5 (CDH5) (AA 621-660) antibody (ABIN729343) Image provided by One World Lab validation program. A549 cells probed with Rabbit Ant...
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