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Collagen IV 抗体 (AA 1401-1500) (Biotin)

COL4 适用: 人, 小鼠, 大鼠, 兔 ELISA, WB, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN728415
发货至: 中国
  • 抗原 See all Collagen IV (COL4) 抗体
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    抗原表位
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1401-1500
    适用
    • 90
    • 42
    • 40
    • 23
    • 15
    • 11
    • 5
    • 2
    人, 小鼠, 大鼠, 兔
    宿主
    • 59
    • 27
    • 13
    克隆类型
    • 71
    • 28
    多克隆
    标记
    • 50
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Collagen IV antibody is conjugated to Biotin
    应用范围
    • 61
    • 49
    • 30
    • 29
    • 27
    • 26
    • 26
    • 26
    • 20
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody has 79 % cross reactivity with Collagen alpha-5(IV) chain.
    交叉反应
    人, 小鼠, 兔, 大鼠
    预测反应
    Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
    亚型
    IgG
    Top Product
    Discover our top product COL4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    别名
    Collagen 4 (COL4 产品)
    别名
    collagen, type IV antibody, Let-2 antibody
    背景

    Synonyms: Bru, Raw, Svc, Col4a-1, Del(8)44H, Collagen alpha-1(IV) chain, Col4a1

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).

    基因ID
    12826
    UniProt
    P02463
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