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JAK3 抗体 (C-Term)

The 兔 多克隆 anti-JAK3 antibody is suitable to detect JAK3 in samples from 人. It has been validated for WB.
产品编号 ABIN7464817
发货至: 中国
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Quick Overview for JAK3 抗体 (C-Term) (ABIN7464817)

抗原

See all JAK3 抗体
JAK3 (Janus Kinase 3 (JAK3))

适用

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宿主

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克隆类型

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多克隆

标记

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This JAK3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

KO Validated
  • 抗原表位

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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human JAK3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: NCI-H929

    Validation: Comparison, KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.11 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    JAK3 (Janus Kinase 3 (JAK3))

    别名

    Janus kinase 3

    背景

    Janus kinase 3 , JAK-3 , JAK3_HUMAN , JAKL , L-JAK , LJAK,The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]

    分子量

    125 kDa

    基因ID

    3718

    UniProt

    P52333

    途径

    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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