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CLOCK 抗体

CLOCK 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7266414
发货至: 中国
  • 抗原 See all CLOCK 抗体
    CLOCK (Clock Homolog (Mouse) (CLOCK))
    适用
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    宿主
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    克隆类型
    • 38
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    单克隆
    标记
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    This CLOCK antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    原理
    CLOCK Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human CLOCK
    亚型
    IgG
    Top Product
    Discover our top product CLOCK Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CLOCK (Clock Homolog (Mouse) (CLOCK))
    别名
    CLOCK (CLOCK 产品)
    别名
    CG7391 antibody, CLK antibody, CLOCK antibody, Dmel\\CG7391 antibody, Jerk antibody, Jrk antibody, PAS1 antibody, bHLHe10 antibody, clk antibody, clock antibody, dCLK antibody, dCLK/JRK antibody, dCLOCK antibody, dClck antibody, dClk antibody, dClock antibody, dclk antibody, jrk antibody, Xclk antibody, XClock antibody, zCLOCK1 antibody, zfCLOCK1 antibody, 5330400M04Rik antibody, KAT13D antibody, bHLHe8 antibody, mKIAA0334 antibody, Clock antibody, clock circadian regulator antibody, clock homolog (mouse) antibody, clock circadian regulator a antibody, circadian locomotor output cycles kaput antibody, clock circadian regulator L homeolog antibody, Clk antibody, CLOCK antibody, clock antibody, clocka antibody, Clock antibody, clock.L antibody
    背景
    The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],KAT13D, bHLHe8,Blood,Blood_Blood Pressure regulation,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Lipid Metabolism,Neuroscience,Signal Transduction,Transcription Factors,CLOCK
    分子量
    95kDa
    基因ID
    9575
    UniProt
    O15516
    途径
    Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
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