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TMPRSS2 抗体 (AA 301-400)

TMPRSS2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN716876
发货至: 中国
  • 抗原 See all TMPRSS2 抗体
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    抗原表位
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 41
    • 28
    • 20
    • 6
    • 6
    • 1
    人, 小鼠, 大鼠
    宿主
    • 37
    • 4
    • 1
    克隆类型
    • 39
    • 3
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMPRSS2 antibody is un-conjugated
    应用范围
    • 42
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TMPRSS2
    亚型
    IgG
    Top Product
    Discover our top product TMPRSS2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
    别名
    Prss10 (TMPRSS2 产品)
    别名
    PP9284 antibody, PRSS10 antibody, D16Ertd61e antibody, transmembrane protease serine 2-like antibody, transmembrane protease, serine 2 antibody, LOC100739411 antibody, TMPRSS2 antibody, Tmprss2 antibody
    背景

    Synonyms: PP9284, PRSS10, Transmembrane protease serine 2, Serine protease 10, TMPRSS2

    Background: Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions, spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9), involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.

    基因ID
    7113
    UniProt
    O15393
    途径
    SARS-CoV-2 Protein Interactome
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