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- 抗原 See all SMUG1 抗体
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMUG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of Human SMUG1.
- 亚型
- IgG
- Top Product
- Discover our top product SMUG1 Primary Antibody
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anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (N-Term) antibody
Verified SMUG1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-177) antibodySMUG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 2-78) antibodySMUG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (Internal Region) antibodySMUG1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-270) antibodySMUG1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) antibodySMUG1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-177) antibodySMUG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 110-159) antibodySMUG1 适用: 人, 小鼠, 大鼠, 猴, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-270) antibodySMUG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (Center) antibodySMUG1 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
- 别名
- SMUG1 (SMUG1 产品)
- 别名
- SMUG1 antibody, xsmug1 antibody, 1200013B09Rik antibody, A930006H09Rik antibody, C85220 antibody, FDG antibody, HMUDG antibody, UNG3 antibody, single-strand-selective monofunctional uracil-DNA glycosylase 1 antibody, single-strand selective monofunctional uracil DNA glycosylase antibody, single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog antibody, SMUG1 antibody, smug1 antibody, smuG1 antibody, smuG antibody, LOC5577584 antibody, CpipJ_CPIJ002767 antibody, Smug1 antibody, smug1.L antibody
- 背景
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Background: Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine) and other oxidized damage. The activity is damage specificity and salt concentration-dependent. The general order of the preference for ssDNA and dsDNA is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at the low salt concentration. At the high concentration dsDNA (G pair) > dsDNA (A pair) > ssDNA.
Ide H., Biochemistry 42:5003-5012(2003).
Sugano S., Nat. Genet. 36:40-45(2004).
Venter J.C., Submitted (JUL-2005).Aliases: FDG antibody, HMUDG antibody, MGC104370 antibody, Single strand selective monofunctional uracil DNA glycosylase 1 antibody, Single strand selective monofunctional uracil DNA glycosylase antibody, Single-strand selective monofunctional uracil DNA glycosylase antibody, SMUG 1 antibody, Smug1 antibody, SMUG1 protein antibody, SMUG1_HUMAN antibody, UNG 3 antibody, UNG3 antibody
- UniProt
- Q53HV7
- 途径
- DNA Damage Repair
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