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VPS26A 抗体 (AA 21-180) (Biotin)

VPS26A 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7175290
发货至: 中国
  • 抗原 See all VPS26A 抗体
    VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))
    抗原表位
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 21-180
    适用
    • 41
    • 16
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 2
    • 1
    克隆类型
    • 32
    • 10
    多克隆
    标记
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This VPS26A antibody is conjugated to Biotin
    应用范围
    • 24
    • 15
    • 8
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Vacuolar protein sorting-associated protein 26A protein (21-180AA)
    亚型
    IgG
    Top Product
    Discover our top product VPS26A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))
    别名
    VPS26A (VPS26A 产品)
    别名
    HB58 antibody, Hbeta58 antibody, PEP8A antibody, VPS26 antibody, AA407240 antibody, Vps26 antibody, VPS26A antibody, MNC6.7 antibody, MNC6_7 antibody, vacuolar protein sorting 26A antibody, DKFZp459G2011 antibody, hb58 antibody, hbeta58 antibody, pep8a antibody, vps26 antibody, vps26a antibody, wu:fc67e06 antibody, zgc:56673 antibody, VPS26, retromer complex component A antibody, VPS26 retromer complex component A antibody, vacuolar protein sorting 26A antibody, vacuolar protein sorting 26 antibody, vacuolar protein sorting homolog26 antibody, vacuolar protein sorting 26 homolog A (S. pombe) pseudogene antibody, VPS26 retromer complex component A S homeolog antibody, VPS26 retromer complex component A L homeolog antibody, vacuolar protein sorting 26 homolog A (S. pombe) antibody, VPS26A antibody, Vps26a antibody, LOC692917 antibody, vpsh26 antibody, LOC100147400 antibody, vps26a.S antibody, vps26a.L antibody, vps26a antibody
    背景

    Background: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins (Probable). The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (Probable). Required for retrograde transport of lysosomal enzyme receptor IGF2R (PubMed:15078902, PubMed:15078903). Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) (PubMed:15247922). Required for the endosomal localization of WASHC2A (indicative for the WASH complex) (PubMed:22070227). Required for the endosomal localization of TBC1D5 (PubMed:20923837). Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP (PubMed:22279231). Involved in retromer-independent lysosomal sorting of F2R (PubMed:16407403). Involved in recycling of ADRB2 (PubMed:21602791). Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins (By similarity).

    Aliases: FLJ12930 antibody, HB 58 antibody, HB58 antibody, Hbeta 58 antibody, Hbeta 58 homolog antibody, Hbeta58 antibody, Hbeta58 homolog antibody, hVPS 26 antibody, hVPS26 antibody, MGC94168 antibody, PEP 8A antibody, PEP8A antibody, Vacuolar protein sorting 26 A antibody, Vacuolar protein sorting 26 antibody, Vacuolar protein sorting 26 homolog A antibody, Vacuolar protein sorting 26 homolog A S. pombe antibody, Vacuolar protein sorting 26 homolog A yeast antibody, Vacuolar protein sorting 26 yeast antibody, Vacuolar protein sorting 26 yeast homolog antibody, Vacuolar protein sorting 26A antibody, Vacuolar protein sorting associated protein 26A antibody, Vacuolar protein sorting-associated protein 26A antibody, Vesicle protein sorting 26 antibody, Vesicle protein sorting 26A antibody, VP26A_HUMAN antibody, VPS 26 antibody, VPS 26A antibody, VPS26A antibody

    UniProt
    O75436
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