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- 抗原 See all PTPRB 抗体
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
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抗原表位
- AA 1758-1997
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPRB antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Receptor-type tyrosine-protein phosphatase beta protein (1758-1997AA)
- 亚型
- IgG
- Top Product
- Discover our top product PTPRB Primary Antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1041-1310) antibody
PTPRB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1655-1918) antibodyPTPRB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1214-1463) antibodyPTPRB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (Internal Region) antibodyVerified PTPRB 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (N-Term) antibodyPTPRB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- 别名
- PTPRB (PTPRB 产品)
- 别名
- PTPRB antibody, HPTP-BETA antibody, HPTPB antibody, PTPB antibody, R-PTP-BETA antibody, VEPTP antibody, 3230402H02Rik antibody, C130094E24 antibody, Ptpz antibody, Rptpb antibody, VE-PTP antibody, Veptp antibody, protein tyrosine phosphatase, receptor type B antibody, receptor-type tyrosine-protein phosphatase beta antibody, protein tyrosine phosphatase, receptor type, B antibody, PTPRB antibody, LOC100380677 antibody, Ptprb antibody
- 背景
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Background: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity).
Aliases: HPTP BETA antibody, HPTPB antibody, Phosphacan receptor type B antibody, Protein tyrosine phosphatase receptor type B antibody, Protein-tyrosine phosphatase beta antibody, PTPB antibody, Ptprb antibody, PTPRB_HUMAN antibody, R PTP BETA antibody, R-PTP-beta antibody, Receptor-type tyrosine-protein phosphatase beta antibody, RPTPB antibody, Vascular endothelial protein tyrosine phosphatase antibody, VE-PTP antibody
- UniProt
- P23467
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